Slay the Spire 2

Potions Database

63 potions with complete effects and usage tips

Potions provide powerful one-time effects that can turn the tide of battle. Master potion selection and timing to maximize your run's potential.

63
Total Potions
20
Common
20
Uncommon
20
Rare
63 / 63
Ashwater

Ashwater

Exhaust any number of cards in your Hand.

UncommonIronclad
Attack Potion

Attack Potion

Choose 1 of 3 random Attack cards to add into your Hand. It's free to play this turn.

Common
Beetle Juice

Beetle Juice

Enemy's attacks deal 30% less damage for the next 4 turns.

Rare
Blessing of the Forge

Blessing of the Forge

Upgrade all cards in your Hand for the rest of combat.

Uncommon
Block Potion

Block Potion

Gain 12 Block.

Common
Blood Potion

Blood Potion

Heal for [green]20%[/green] of your Max HP.

CommonIronclad
Bone Brew

Bone Brew

Summon 15.

UncommonNecrobinder
Bottled Potential

Bottled Potential

Shuffle ALL your cards into your Draw Pile. Draw 5 cards.

Rare
Clarity Extract

Clarity Extract

Draw 1 card. At the start of your next 3 turns, draw 1 additional card.

Uncommon
Colorless Potion

Colorless Potion

Choose 1 of 3 random Colorless cards to add into your Hand. It's free to play this turn.

Common
Cosmic Concoction

Cosmic Concoction

Add 3 Upgraded Colorless cards into your Hand.

RareRegent
Cunning Potion

Cunning Potion

Add 3 Upgraded Shivs into your Hand.

UncommonSilent
Cure All

Cure All

Gain [energy:1]. Draw 2 cards.

Uncommon
Dexterity Potion

Dexterity Potion

Gain 2 Dexterity.

Common
Distilled Chaos

Distilled Chaos

Play the top 3 cards of your Draw Pile.

Rare
Droplet of Precognition

Droplet of Precognition

Choose a card in your Draw Pile and add it into your Hand.

Rare
Duplicator

Duplicator

This turn, your next card is played an extra time.

Uncommon
Energy Potion

Energy Potion

Gain [energy:2].

Common
Entropic Brew

Entropic Brew

Fill all your empty potion slots with random potions.

Rare
Essence of Darkness

Essence of Darkness

Channel a Dark for each of your Orb Slots.

RareDefect
Explosive Ampoule

Explosive Ampoule

Deal 10 damage to ALL enemies.

Common
Fairy in a Bottle

Fairy in a Bottle

When you would die, instead this potion is discarded and you heal to 30% of your Max HP.

Rare
Fire Potion

Fire Potion

Deal 20 damage.

Common
Flex Potion

Flex Potion

Gain 5 Strength. At the end of your turn, lose 5 Strength.

Common
Focus Potion

Focus Potion

Gain 2 Focus.

CommonDefect
Fortifier

Fortifier

Triple your Block.

Uncommon
Foul Potion

Foul Potion

Deal 12 damage to EVERYONE. Can be thrown at the Merchant for 100 Gold instead.

EventShared
Fruit Juice

Fruit Juice

Gain 5 Max HP.

Rare
Fysh Oil

Fysh Oil

Gain 1 Strength and 1 Dexterity.

Uncommon
Gambler's Brew

Gambler's Brew

Discard any number of cards, then draw that many.

Uncommon
Ghost in a Jar

Ghost in a Jar

Gain 1 Intangible.

RareSilent
Gigantification Potion

Gigantification Potion

The next Attack you play deals triple damage.

Rare
Glowwater Potion

Glowwater Potion

Exhaust your Hand. Draw 10 cards.

EventShared
Heart of Iron

Heart of Iron

Gain 7 Plating.

Uncommon
King's Courage

King's Courage

Forge 15.

UncommonRegent
Liquid Bronze

Liquid Bronze

Gain 3 Thorns.

Uncommon
Liquid Memories

Liquid Memories

Put a card from your Discard Pile into your Hand. It costs 0 [energy:1] this turn.

Rare
Lucky Tonic

Lucky Tonic

Gain 1 Buffer.

Rare
Mazaleth's Gift

Mazaleth's Gift

Gain 1 Ritual.

Rare
Orobic Acid

Orobic Acid

Add a random Attack, Skill, and Power into your Hand. They're free to play this turn.

Rare
Poison Potion

Poison Potion

Apply 6 Poison.

CommonSilent
Pot of Ghouls

Pot of Ghouls

Add 2 Souls into your Hand.

RareNecrobinder
Potion of Binding

Potion of Binding

Apply 1 Weak and 1 Vulnerable to ALL enemies.

Uncommon
Potion of Capacity

Potion of Capacity

Gain 2 Orb Slots.

UncommonDefect
Potion of Doom

Potion of Doom

Apply 33 Doom.

CommonNecrobinder
Potion-Shaped Rock

Potion-Shaped Rock

Deal 15 damage.

Token
Powdered Demise

Powdered Demise

Enemy loses 9 HP at the end of each of its turns.

Uncommon
Power Potion

Power Potion

Choose 1 of 3 random Power cards to add into your Hand. It's free to play this turn.

Common
Radiant Tincture

Radiant Tincture

Gain [energy:1]. Gain an additional [energy:1] at the start of your next 3 turns.

Uncommon
Regen Potion

Regen Potion

Gain [green]5[/green] Regen.

Uncommon
Shackling Potion

Shackling Potion

ALL enemies lose 7 Strength this turn.

Rare
Ship in a Bottle

Ship in a Bottle

Gain 10 Block. Next turn, gain 10 Block.

Rare
Skill Potion

Skill Potion

Choose 1 of 3 random Skill cards to add into your Hand. It's free to play this turn.

Common
Snecko Oil

Snecko Oil

Draw 7 cards. Randomize the cost of cards in your Hand this turn.

Rare
Soldier's Stew

Soldier's Stew

All cards containing Strike gain 1 Replay this combat.

RareIronclad
Speed Potion

Speed Potion

Gain 5 Dexterity. At the end of your turn, lose 5 Dexterity.

Common
Stable Serum

Stable Serum

Retain your Hand for 2 turns.

Uncommon
Star Potion

Star Potion

Gain [star:3].

CommonRegent
Strength Potion

Strength Potion

Gain 2 Strength.

Common
Swift Potion

Swift Potion

Draw 3 cards.

Common
Touch of Insanity

Touch of Insanity

Choose a card in your Hand. It is free to play this combat.

Uncommon
Vulnerable Potion

Vulnerable Potion

Apply 3 Vulnerable.

Common
Weak Potion

Weak Potion

Apply 3 Weak.

Common