Card Tier List
Slay the Spire 2 — All 504 Cards Ranked S to F
Every card evaluated by power level, cost efficiency, and overall run impact. Filter by card type or rarity to find the best picks for your build.
Tier Definitions
Game-defining cards. Near-auto-pick regardless of build.
Excellent cards. Strong pickups that fit most builds.
Solid cards. Good value in the right deck.
Situational. Only pick if it supports your specific build.
Weak cards. Avoid unless you have a specific combo.
Skip these. Nearly always a dead pick.
Card Type
Rarity

Abrasive
Power · Rare

Accelerant
Power · Rare

Afterimage
Power · Rare

Aggression
Power · Rare

Apotheosis
Skill · Ancient

Apparition
Skill · Ancient

Arsenal
Power · Rare

Assassinate
Attack · Rare

Barricade
Power · Rare
Beacon of Hope
Power · Rare

Biased Cognition
Power · Ancient

Bludgeon
Attack · Uncommon

Body Slam
Attack · Common

Break
Attack · Ancient

Brightest Flame
Skill · Ancient

Buffer
Power · Rare

Calamity
Power · Rare

Call of the Void
Power · Rare

Consuming Shadow
Power · Rare

Coolant
Power · Rare

Corruption
Power · Ancient

Crash Landing
Attack · Rare

Creative AI
Power · Rare

Crimson Mantle
Power · Rare

Cruelty
Power · Rare

Dark Embrace
Power · Rare

Defragment
Power · Rare

Demesne
Power · Rare

Demon Form
Power · Rare

Devour Life
Power · Rare

Echo Form
Power · Rare

Entropy
Power · Rare

Envenom
Power · Rare

Eternal Armor
Power · Rare

Fan of Knives
Power · Rare

Feed
Attack · Rare

Feel No Pain
Power · Uncommon

Fiend Fire
Attack · Rare

Forbidden Grimoire
Power · Ancient

Genesis
Power · Rare

Grand Finale
Attack · Rare

Hammer Time
Power · Rare

Hellraiser
Power · Rare

Hyperbeam
Attack · Rare

Impervious
Skill · Rare

Inflame
Power · Uncommon

Juggernaut
Power · Rare

Machine Learning
Power · Rare

Make It So
Attack · Rare

Master Planner
Power · Rare

Maul
Attack · Ancient

Mayhem
Power · Rare

Meteor Shower
Attack · Ancient

Misery
Attack · Rare

Monarch's Gaze
Power · Rare

Necro Mastery
Power · Rare

Neow's Fury
Attack · Ancient

Neurosurge
Power · Rare

Neutron Aegis
Power · Rare

Nostalgia
Power · Rare

Offering
Skill · Rare

Pact's End
Attack · Rare

Protector
Attack · Ancient

Pyre
Power · Rare

Quadcast
Skill · Ancient

Rage
Skill · Uncommon

Reaper Form
Power · Rare

Relax
Skill · Ancient

Rolling Boulder
Power · Rare

Royalties
Power · Rare

Salvo
Attack · Rare

Second Wind
Skill · Uncommon

Seeking Edge
Power · Rare

Sentry Mode
Power · Rare

Serpent Form
Power · Rare

Sneaky
Power · Rare

Spinner
Power · Rare

Spirit of Ash
Power · Rare

Suppress
Attack · Ancient

Sword Sage
Power · Rare

Tank
Power · Rare

The Sealed Throne
Power · Ancient

Tools of the Trade
Power · Rare
Tracking
Power · Rare

Trash to Treasure
Power · Rare

Tyranny
Power · Rare

Unmovable
Power · Rare

Void Form
Power · Rare

Whirlwind
Attack · Uncommon

Whistle
Attack · Ancient

Wish
Skill · Ancient

Wraith Form
Power · Ancient

Accuracy
Power · Uncommon

Adaptive Strike
Attack · Rare

Adrenaline
Skill · Rare

Alchemize
Skill · Rare

All for One
Attack · Rare

Anger
Attack · Common

Anointed
Skill · Rare

Armaments
Skill · Common

Automation
Power · Uncommon

Backstab
Attack · Uncommon

Banshee's Cry
Attack · Rare

Battle Trance
Skill · Uncommon

Beat Down
Skill · Rare

Beat into Shape
Attack · Rare

Big Bang
Skill · Rare

Black Hole
Power · Uncommon

Blade of Ink
Skill · Rare

Bolas
Attack · Rare

Bombardment
Attack · Rare

Boot Sequence
Skill · Uncommon

Brand
Skill · Rare

Bulk Up
Power · Uncommon

Bullet Time
Skill · Rare

Bundle of Joy
Skill · Rare

Burning Pact
Skill · Uncommon

Burst
Skill · Rare

Bury
Attack · Uncommon

Calcify
Power · Uncommon

Capacitor
Power · Uncommon

Cascade
Skill · Rare

Child of the Stars
Power · Uncommon

Colossus
Skill · Rare

Comet
Attack · Rare

Conflagration
Attack · Rare

Corrosive Wave
Skill · Rare

Countdown
Power · Uncommon

Danse Macabre
Power · Uncommon

Decisions, Decisions
Skill · Rare

Dramatic Entrance
Attack · Uncommon

Drum of Battle
Power · Uncommon

Dying Star
Attack · Rare

Echoing Slash
Attack · Rare

Eidolon
Skill · Rare

End of Days
Skill · Rare

Eradicate
Attack · Rare

Fasten
Power · Uncommon

Feral
Power · Uncommon

Fight Through
Skill · Uncommon

Flak Cannon
Attack · Rare

Flame Barrier
Skill · Uncommon

Flash of Steel
Attack · Uncommon

Footwork
Power · Uncommon

Foregone Conclusion
Skill · Rare

Friendship
Power · Uncommon

FTL
Attack · Uncommon

Furnace
Power · Uncommon

Genetic Algorithm
Skill · Rare

Glimpse Beyond
Skill · Rare

Gold Axe
Attack · Rare

GUARDS!!!
Skill · Rare

Hailstorm
Power · Uncommon

Hand of Greed
Attack · Rare

Hang
Attack · Rare

Haunt
Power · Uncommon

Heavenly Drill
Attack · Rare

Heirloom Hammer
Attack · Rare

Helix Drill
Attack · Rare

Hemokinesis
Attack · Uncommon

Hidden Gem
Skill · Rare

I Am Invincible
Skill · Rare

Ice Lance
Attack · Rare

Ignition
Skill · Rare

Infernal Blade
Skill · Uncommon

Inferno
Power · Uncommon

Infinite Blades
Power · Uncommon

Iron Wave
Attack · Common

Iteration
Power · Uncommon

Jackpot
Attack · Rare

Juggling
Power · Uncommon

Knife Trap
Skill · Rare

Knockdown
Attack · Rare

Knockout Blow
Attack · Uncommon

Lethality
Power · Uncommon

Lift
Skill · Uncommon

Loop
Power · Uncommon

Malaise
Skill · Rare

Mangle
Attack · Rare

Master of Strategy
Skill · Rare

Meteor Strike
Attack · Rare

Mimic
Skill · Rare

Modded
Skill · Rare

Multi-Cast
Skill · Rare

Murder
Attack · Rare

Nightmare
Skill · Rare

Noxious Fumes
Power · Uncommon

Oblivion
Skill · Rare

Omnislice
Attack · Uncommon

One-Two Punch
Skill · Rare

Orbit
Power · Uncommon

Outbreak
Power · Uncommon

Pagestorm
Power · Uncommon

Pale Blue Dot
Power · Uncommon

Panache
Power · Uncommon

Panic Button
Skill · Uncommon

Parry
Power · Uncommon

Perfected Strike
Attack · Common

Phantom Blades
Power · Uncommon

Pillar of Creation
Power · Uncommon

Pommel Strike
Attack · Common

Prep Time
Power · Uncommon

Primal Force
Skill · Rare

Prowess
Power · Uncommon

Rainbow
Skill · Rare

Rally
Skill · Rare

Rampage
Attack · Uncommon

Reanimate
Skill · Rare

Reboot
Skill · Rare

Rend
Attack · Rare

Rip and Tear
Attack · Uncommon

Rupture
Power · Uncommon

Sacrifice
Skill · Rare

Scrawl
Skill · Rare

Seance
Skill · Rare

Secret Technique
Skill · Rare

Secret Weapon
Skill · Rare

Seven Stars
Attack · Rare

Shadow Step
Skill · Rare

Shadowmeld
Skill · Rare

Shared Fate
Skill · Rare

Shatter
Attack · Rare

Shockwave
Skill · Uncommon

Shroud
Power · Uncommon

Signal Boost
Skill · Rare

Sleight of Flesh
Power · Uncommon

Smokestack
Power · Uncommon

Soul Storm
Attack · Rare

Spectrum Shift
Power · Uncommon

Speedster
Power · Uncommon

Spite
Attack · Uncommon

Squeeze
Attack · Rare

Stampede
Power · Uncommon

Stardust
Attack · Uncommon

Stoke
Skill · Rare

Stone Armor
Power · Uncommon

Storm
Power · Uncommon

Storm of Steel
Skill · Rare

Stratagem
Power · Uncommon

Subroutine
Power · Uncommon

Supercritical
Skill · Rare

Sword Boomerang
Attack · Common

Tear Asunder
Attack · Rare

The Gambit
Skill · Rare

The Hunt
Attack · Rare

The Scythe
Attack · Rare

The Smith
Skill · Rare

Thrash
Attack · Rare

Thrumming Hatchet
Attack · Uncommon

Thunder
Power · Uncommon

Time's Up
Attack · Rare

Transfigure
Skill · Rare

Twin Strike
Attack · Common

Ultimate Defend
Skill · Uncommon

Ultimate Strike
Attack · Uncommon

Undeath
Skill · Rare

Uppercut
Attack · Uncommon

Veilpiercer
Attack · Uncommon

Vicious
Power · Uncommon

Voltaic
Skill · Rare

Well-Laid Plans
Power · Uncommon

Blight Strike
Attack · Common

Blood Wall
Skill · Common

Blur
Skill · Uncommon

Bone Shards
Attack · Uncommon

Boost Away
Skill · Common

Breakthrough
Attack · Common

Bulwark
Skill · Uncommon

Cinder
Attack · Common

Collision Course
Attack · Common

Compact
Skill · Uncommon

Dagger Spray
Attack · Common

Dagger Throw
Attack · Common

Dash
Attack · Uncommon

Death's Door
Skill · Uncommon

Debilitate
Attack · Uncommon

Defile
Attack · Common

Deflect
Skill · Common

Delay
Skill · Uncommon

Dismantle
Attack · Uncommon

Drain Power
Attack · Common

Equilibrium
Skill · Uncommon

Escape Plan
Skill · Uncommon

Evil Eye
Skill · Uncommon

Fetch
Attack · Uncommon

Finesse
Skill · Uncommon

Finisher
Attack · Uncommon

Fisticuffs
Attack · Uncommon

Flechettes
Attack · Uncommon

Focused Strike
Attack · Common

Follow Through
Attack · Uncommon

Glasswork
Skill · Uncommon

Grapple
Attack · Uncommon

Grave Warden
Skill · Common

Hand Trick
Skill · Uncommon

Headbutt
Attack · Common

Hegemony
Attack · Uncommon

High Five
Attack · Uncommon

Howl from Beyond
Attack · Uncommon

Intercept
Skill · Uncommon

Kingly Kick
Attack · Uncommon

Kingly Punch
Attack · Uncommon

Leap
Skill · Common

Leg Sweep
Skill · Uncommon

Lunar Blast
Attack · Uncommon

Manifest Authority
Skill · Uncommon

Molten Fist
Attack · Common

Momentum Strike
Attack · Common

Null
Attack · Uncommon

Patter
Skill · Common

Photon Cut
Attack · Common

Pillage
Attack · Uncommon

Pinpoint
Attack · Uncommon

Poke
Attack · Common

Pounce
Attack · Uncommon

Predator
Attack · Uncommon

Pull from Below
Attack · Uncommon

Radiate
Attack · Uncommon

Rattle
Attack · Uncommon

Reap
Attack · Common

Reave
Attack · Common

Refract
Attack · Uncommon

Right Hand Hand
Attack · Uncommon

Rocket Punch
Attack · Uncommon

Scrape
Attack · Uncommon

Sculpting Strike
Attack · Common

Seeker Strike
Attack · Uncommon

Severance
Attack · Uncommon

Shadow Shield
Skill · Uncommon

Shining Strike
Attack · Uncommon

Shrug It Off
Skill · Common

Sic 'Em
Attack · Uncommon

Slice
Attack · Common

Solar Strike
Attack · Common

Sow
Attack · Common

Strangle
Attack · Uncommon

Sucker Punch
Attack · Common

Sunder
Attack · Uncommon

Synthesis
Attack · Uncommon

Tag Team
Attack · Uncommon

Taunt
Skill · Uncommon

Tesla Coil
Attack · Uncommon

Unrelenting
Attack · Uncommon

Volley
Attack · Uncommon

Alignment
Skill · Uncommon

Ashen Strike
Attack · Uncommon

Astral Pulse
Attack · Common

Backflip
Skill · Common

Ball Lightning
Attack · Common

Barrage
Attack · Common

Beam Cell
Attack · Common

BEGONE!
Attack · Common

Believe in You
Skill · Uncommon

Borrowed Time
Skill · Uncommon

Bouncing Flask
Skill · Uncommon

Bubble Bubble
Skill · Uncommon

Bully
Attack · Uncommon

Calculated Gamble
Skill · Uncommon

Capture Spirit
Skill · Uncommon

Catastrophe
Skill · Uncommon

Chaos
Skill · Uncommon

Charge Battery
Skill · Common

CHARGE!!
Skill · Uncommon

Chill
Skill · Uncommon

Claw
Attack · Common

Cleanse
Skill · Uncommon

Cloak and Dagger
Skill · Common

Cloak of Stars
Skill · Common

Cold Snap
Attack · Common

Compile Driver
Attack · Common

Conqueror
Skill · Uncommon

Convergence
Skill · Uncommon

Coordinate
Skill · Uncommon

Cosmic Indifference
Skill · Common

Crush Under
Attack · Common

Dark Shackles
Skill · Uncommon

Darkness
Skill · Uncommon

Death March
Attack · Uncommon

Deathbringer
Skill · Uncommon

Defy
Skill · Common

Demonic Shield
Skill · Uncommon

Devastate
Attack · Uncommon

Dirge
Skill · Uncommon

Discovery
Skill · Uncommon

Dodge and Roll
Skill · Common

Dominate
Skill · Uncommon

Double Energy
Skill · Uncommon

Dredge
Skill · Uncommon

Energy Surge
Skill · Uncommon

Enfeebling Touch
Skill · Uncommon

Expect a Fight
Skill · Uncommon

Expertise
Skill · Uncommon

Expose
Skill · Uncommon

Fear
Attack · Common

Fight Me!
Attack · Uncommon

Flanking
Skill · Uncommon

Flatten
Attack · Common

Flick-Flack
Attack · Common

Forgotten Ritual
Skill · Uncommon

Fusion
Skill · Uncommon

Gamma Blast
Attack · Uncommon

Gang Up
Attack · Uncommon

Gather Light
Skill · Common

Glacier
Skill · Uncommon

Glimmer
Skill · Uncommon

Glitterstream
Skill · Common

Go for the Eyes
Attack · Common

Graveblast
Attack · Common

Gunk Up
Attack · Common

Haze
Skill · Uncommon

Hidden Daggers
Skill · Uncommon

Huddle Up
Skill · Uncommon

Impatience
Skill · Uncommon

Jack of All Trades
Skill · Uncommon

Largesse
Skill · Uncommon

Leading Strike
Attack · Common

Legion of Bone
Skill · Uncommon

Lightning Rod
Skill · Common

Melancholy
Skill · Uncommon

Memento Mori
Attack · Uncommon

Mind Blast
Attack · Uncommon

Mirage
Skill · Uncommon

Monologue
Skill · Uncommon

Negative Pulse
Skill · Common

No Escape
Skill · Uncommon

Overclock
Skill · Uncommon

Parse
Skill · Uncommon

Particle Wall
Skill · Uncommon

Poisoned Stab
Attack · Common

Precise Cut
Attack · Uncommon

Production
Skill · Uncommon

Prolong
Skill · Uncommon

Prophesize
Skill · Uncommon

Purity
Skill · Uncommon

Putrefy
Skill · Uncommon

Quasar
Skill · Uncommon

Reflect
Skill · Uncommon

Reflex
Skill · Uncommon

Resonance
Skill · Uncommon

Restlessness
Skill · Uncommon

Royal Gamble
Skill · Uncommon

Scavenge
Skill · Uncommon

Setup Strike
Attack · Common

Skewer
Attack · Uncommon

Skim
Skill · Uncommon

Snap
Attack · Common

Splash
Skill · Uncommon

Spur
Skill · Uncommon

Stomp
Attack · Uncommon

Summon Forth
Skill · Uncommon

Supermassive
Attack · Uncommon

Sweeping Beam
Attack · Common

Synchronize
Skill · Uncommon

Tactician
Skill · Uncommon

Tempest
Skill · Uncommon

Terraforming
Skill · Uncommon

The Bomb
Skill · Uncommon

Thinking Ahead
Skill · Uncommon

Thunderclap
Attack · Common

True Grit
Skill · Common

Untouchable
Skill · Common

Up My Sleeve
Skill · Uncommon

Uproar
Attack · Common

White Noise
Skill · Uncommon

Wrought in War
Attack · Common

Acrobatics
Skill · Common

Afterlife
Skill · Common

Anticipate
Skill · Common

Bash
Attack · Basic

Blade Dance
Skill · Common

Bloodletting
Skill · Common

Bodyguard
Skill · Basic

Celestial Might
Attack · Common

Coolheaded
Skill · Common

Crescent Spear
Attack · Common

Deadly Poison
Skill · Common

Defend
Skill · Basic

Dualcast
Skill · Basic

Falling Star
Attack · Basic

Glow
Skill · Common

Guiding Star
Attack · Common

Havoc
Skill · Common

Hidden Cache
Skill · Common

Hologram
Skill · Common

Hotfix
Skill · Common

Invoke
Skill · Common

Know Thy Place
Skill · Common

Neutralize
Attack · Basic

Piercing Wail
Skill · Common

Prepared
Skill · Common

Pull Aggro
Skill · Common

Refine Blade
Skill · Common

Ricochet
Attack · Common

Scourge
Skill · Common

Snakebite
Skill · Common

Spoils of Battle
Skill · Common

Strike
Attack · Basic

Survivor
Skill · Basic

Tremble
Skill · Common

TURBO
Skill · Common

Unleash
Attack · Basic

Venerate
Skill · Basic

Wisp
Skill · Common

Zap
Skill · Basic
No cards match current filters.
Disclaimer: Tier ratings reflect general power level and versatility. Card strength varies with deck archetype, current relics, and run context. Always consider synergies before picking.